AMIBag-S

The human lens is contained in a shell made of collagen fibers, the so-called capsular bag. This is suspended from the ciliary muscle via the zonular fibers. Progressive clouding of the lens of the eye (cataract) also reduces visual acuity and contrast vision and, if left untreated, can lead to blindness. The only successful treatment to date is the surgical removal of the clouded natural lens followed by the implantation of an artificial lens (IOL) into the capsular bag. The capsular bag normally remains intact, including its suspension on the zonular fibers, and retains sufficient stability to hold the lens implant.

The capsular bag can be irreversibly damaged by various causes, meaning that stable positioning of an IOL can no longer be guaranteed. A new attachment of the zonular fibers to the capsular bag or the attachment of an artificial capsular bag to the zonular fibers is not yet possible. In such cases, lenses have to be implanted in other implantation locations in the eye, such as in the space between the iris and the capsular bag, the so-called ciliary sulcus, or fixed to the iris. However, these implantation sites are associated with significant disadvantages.
The solution pursued here is an artificial prosthesis for the capsular bag, which can be implanted into the eye in the same way as an IOL and thus offers the option of placing the originally planned IOL in it.